Fakultät/Einheit

• Fakultät Informatik/Mathematik  Fachbereich

Beteiligt an Projekt/Förderung

• 3D-ADAM - Data Mining für die digitale KI-gestützte Identifikation und Prognose (strahlen)-therapeutischer Effekte  Förderung
• Active-Learning in Machine-Learning-Projekten: Evaluation und Handlungsempfehlungen [FORZUG III]  Förderung
• Dimensionsreduktion in Simulationsmodellen für die KI-getriebene Analyse von 3D-Sphäroiden zur Optimierung von Strahlentherapie in der Tumorbehandlung [Verbundprojekt Forzug II]  Förderung
• Innovative Data-Science Methoden für die Systemmedizin: Assistenz bei der Analyse multizellulärer Gewebeorganisation  Förderung
• Rissentstehung und -wachstum in Nietverbindungen unter Berücksichtigung stochastischer Größen (MatEnUm-2)  Förderung
• Stochastische Vielteilchensysteme zur Analyse von Wachstums- und Verdrängungsprozessen  Förderung

Gremientätigkeit

• Fachgruppe Stochastik der Deutschen Mathematiker-Vereinigung  Komittee
• European Society of Mathematical and Theoretical Biology (ESMTB)  Komittee

Publikation (Autor/in)

• 99512419202581  Wissenschaftlicher Artikel
• 99512419302581  Wissenschaftlicher Artikel
• 99512419402581  Wissenschaftlicher Artikel
• 99529319302581  Wissenschaftlicher Artikel
• 99532319402581  Wissenschaftlicher Artikel
• A dynamically diluted alignment model reveals the impact of cell turnover on the plasticity of tissue polarity patterns  Wissenschaftlicher Artikel
• Amoeboid-mesenchymal migration plasticity promotes invasion only in complex heterogeneous microenvironments  Wissenschaftlicher Artikel
• An Emerging Allee Effect Is Critical for Tumor Initiation and Persistence  Wissenschaftlicher Artikel
• Analysis of Individual Cell Trajectories in Lattice-Gas Cellular Automaton Models for Migrating Cell Populations  Wissenschaftlicher Artikel
• Cell adhesion heterogeneity reinforces tumour cell dissemination: novel insights from a mathematical model  Wissenschaftlicher Artikel
• CellTrans: An R Package to Quantify Stochastic Cell State Transitions  Vortrag
• CellTrans: An R Package to Quantify Stochastic Cell State Transitions  Wissenschaftlicher Artikel
• Cellular Potts Models for Interacting Cell Populations: Mathematical Foundation, Challenges, and Future Prospects  Kapitel
• Challenges in modeling interacting and migrating cell populations.  Vortrag
• Efficient Radial-Shell Model for 3D Tumor Spheroid Dynamics with Radiotherapy  Wissenschaftlicher Artikel
• Emerging Allee effect in tumor growth 
• How Does a Single Cell Know When the Liver Has Reached Its Correct Size?  Wissenschaftlicher Artikel
• Image segmentation of treated and untreated tumor spheroids by Fully Convolutional Networks 
• Is cell segregation like oil and water: asymptotic versus transitory regime  Wissenschaftlicher Artikel
• Migration plasticity increases tumor cell dissemination  Vortrag
• Minimal cellular automaton model with heterogeneous cell sizes predicts epithelial colony growth 
• Minimal cellular automaton model with heterogeneous cell sizes predicts epithelial colony growth  Wissenschaftlicher Artikel
• Model-Based Evaluation of Spontaneous Tumor Regression in Pilocytic Astrocytoma  Wissenschaftlicher Artikel
• Model-Based Prediction of an Effective Adhesion Parameter Guiding Multi-Type Cell Segregation  Wissenschaftlicher Artikel
• Modeling age-specific incidence of colon cancer via niche competition  Wissenschaftlicher Artikel
• Modeling collective cell motion: Are on- and off-lattice models equivalent?  Wissenschaftlicher Artikel
• Multi-Scale Analysis of Contact-Dependent Interaction in Tissue Aggregation and Invasion  Kapitel
• Multi-scale modeling in morphogenesis: a critical analysis of the cellular Potts model  Wissenschaftlicher Artikel
• On the statistical power of Baarda's outlier test and some alternative.  Wissenschaftlicher Artikel
• Patterns of Tumor Progression Predict Small and Tissue-Specific Tumor-Originating Niches  Wissenschaftlicher Artikel
• Phenotypic plasticity in tumor growth and dissemination  Vortrag
• Plasticity within Aldehyde Dehydrogenase-Positive Cells Determines Prostate Cancer Radiosensitivity  Wissenschaftlicher Artikel
• Simulation sozioökonomischer Prozesse mit zellulären Automaten - räumliche Analyse des Kundenverhaltens konkurrierender Apotheken  Konferenz-Paper
• Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment  Wissenschaftlicher Artikel
• Supporting data for "Image segmentation of treated and untreated tumor spheroids by Fully Convolutional Networks" 
• The consequences of phenotypic plasticity on tumor growth and dissemination.  Vortrag
• Vectorial active matter on the lattice: polar condensates and nematic filaments  Wissenschaftlicher Artikel
• A Dynamically Diluted Alignment Model Reveals the Impact of Cell Turnover on the Plasticity of Tissue Polarity Patterns  Vortrag
• Analyzing the impact of cell turnover on the plasticity of tissue polarity patterns by cellular automaton modeling: The dynamically diluted alignment model  Vortrag
• Cellular automaton models for analyzing the collective migration of heterogeneous cell populations  Vortrag
• Collective migration of heterogeneous cell populations  Vortrag
• Data-driven quantification of stochastic cell state transitions in tumor cell lines  Vortrag
• Dimension reduction in simulation models for the analysis of 3D spheroids for the optimization of radiotherapy in tumor treatment  Vortrag
• Image segmentation of irradiated tumour spheroids by Fully  Vortrag
• Image segmentation of irradiated tumour spheroids by Fully Convolutional Networks  Vortrag
• Image segmentation of irradiated tumour spheroids by Fully Convolutional Networks  Vortrag
• Image segmentation of treated and untreated tumor spheroids by Fully Convolutional Networks  Wissenschaftlicher Artikel
• Impact of cell migration plasticity on tumor growth and invasion: A cell-based approach  Vortrag
• Is cell segregation like oil and water: asymptotic versus transitory regime  Vortrag
• Is cell segregation like oil and water: asymptotic versus transitory regime  Vortrag
• Model-Based Prediction of an Effective Adhesion Parameter Guiding Multi-Type Cell Segregation  Vortrag
• Model-Based Prediction of an Effective Adhesion Parameter Guiding Multi-Type Cell Segregation  Vortrag
• Model-based prediction of an effective adhesion parameter guiding multi-type cell segregation  Vortrag
• Model-driven inference of the cellular mechanisms in the early phase of tumor development  Vortrag
• Modeling age-specific incidence of colon cancer via niche competition  Vortrag
• Pancreatic cancer cell spheroid control probability assay (SCP) to assess the outcome of single-dose versus clinical-practice fractionated proton irradiation  Vortrag
• Patterns of Tumor Progression Predict Small and Tissue-Specific Tumor-Originating Niches  Vortrag

Betreute Dissertation

• Impact of cell migration plasticity on tumor growth and invasion: cellular automaton modelling, simulation and analysis. Amoeboid-mesenchymal migration plasticity promotes invasion only in complex heterogeneous microenvironments  Abschlussarbeit
• Infering cellular mechanisms of tumor development from tissue-scale data: A Markov chain approach  Abschlussarbeit

ausgewählte Veröffentlichungen

• dokument

  • Emerging Allee effect in tumor growth
  • Image segmentation of treated and untreated tumor spheroids by Fully Convolutional Networks
  • Minimal cellular automaton model with heterogeneous cell sizes predicts epithelial colony growth
  • Supporting data for "Image segmentation of treated and untreated tumor spheroids by Fully Convolutional Networks"

• kapitel

  • Multi-Scale Analysis of Contact-Dependent Interaction in Tissue Aggregation and Invasion 2020
  • Cellular Potts Models for Interacting Cell Populations: Mathematical Foundation, Challenges, and Future Prospects 2018

• wissenschaftlicher artikel

  • Minimal cellular automaton model with heterogeneous cell sizes predicts epithelial colony growth.  Journal of theoretical biology.  2024
  • Efficient Radial-Shell Model for 3D Tumor Spheroid Dynamics with Radiotherapy.  Cancers.  15. 2023
  • Vectorial active matter on the lattice: polar condensates and nematic filaments.  New journal of physics.  25. 2023
  • Is cell segregation like oil and water: asymptotic versus transitory regime.  PLoS computational biology.  18. 2022
  • Modeling age-specific incidence of colon cancer via niche competition.  PLoS computational biology.  18. 2022
  • Plasticity within Aldehyde Dehydrogenase-Positive Cells Determines Prostate Cancer Radiosensitivity.  Molecular cancer research.  20. 2022
  • Model-Based Prediction of an Effective Adhesion Parameter Guiding Multi-Type Cell Segregation.  Entropy (Basel, Switzerland).  23. 2021
  • Modeling collective cell motion: Are on- and off-lattice models equivalent?.  Philosophical Transactions of the Royal Society B.  375. 2020
  • Patterns of Tumor Progression Predict Small and Tissue-Specific Tumor-Originating Niches.  Frontiers in oncology.  8. 2019
  • Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment.  Nature communications.  10. 2019
  • A dynamically diluted alignment model reveals the impact of cell turnover on the plasticity of tissue polarity patterns.  Journal of the Royal Society interface.  14. 2017
  • Amoeboid-mesenchymal migration plasticity promotes invasion only in complex heterogeneous microenvironments.  Scientific reports.  7. 2017
  • Cell adhesion heterogeneity reinforces tumour cell dissemination: novel insights from a mathematical model.  Biology direct.  12. 2017
  • CellTrans: An R Package to Quantify Stochastic Cell State Transitions.  Bioinformatics and biology insights.  11. 2017
  • On the statistical power of Baarda's outlier test and some alternative..  Journal of geodetic science..  7. 2017
  • An Emerging Allee Effect Is Critical for Tumor Initiation and Persistence.  PLoS computational biology.  11. 2015
  • Analysis of Individual Cell Trajectories in Lattice-Gas Cellular Automaton Models for Migrating Cell Populations.  Bulletin of mathematical biology.  77. 2015
  • Model-Based Evaluation of Spontaneous Tumor Regression in Pilocytic Astrocytoma.  PLoS computational biology.  11. 2015
  • How Does a Single Cell Know When the Liver Has Reached Its Correct Size?.  PLOS ONE.  9. 2014
  • Multi-scale modeling in morphogenesis: a critical analysis of the cellular Potts model.  PLOS ONE.  7. 2012

Ausrichter des Events

• Minisymposium MS-13-AM-02 Cell-based models of tumor ecology and evolution
• SIMBA: Saxon Symposium on Informatics and Mathematics in Biological Applications
• Seminar Mathematics of tumor progression
• Seminar Theories of cell aggregation and invasion
• Seminar Trends and Methods in Mathematical Biology
• Seminar in Mathematical Biology: Mathematics of Collective Cell Migration
• Seminar in Mathematical Biology: Mathematics of tumor evolution and ecology
• Summer Solstice Conference on Discrete Models of Complex Systems 2019
• Workshop Data-driven modeling for the analysis of multicellular tissue organisation,

vollständiger Name

• Anja Voß-Böhme